OBJECTIVE: The student will be able to:

1. identify the genotype of the parents
2. identify the genotype of the offspring

There are six combinations of genotypes of the parent cells in determining the genotype of the offspring. Use the following abbreviations when determining the genotypes for hemoglobin in their association with sickle cell disease.

Hb - being normal hemoglobin

HbS - being "abnormal" hemoglobin (carrier)

HbS HbS - being sickle cell disease

PROCEDURE:

1. Divide students so that there are six groups each representing one of the genotype combinations of the parent cells (ovum, sperm)
2. 2 paper cups containing the beans needed to represent the genotypes of the parent cell, label the cups male and female.
3. Choose one bean from each of the cups, this represents the offspring's genotype
4. Repeat step 3 ten times
5. Record the information the data table
6. Answer group data questions
7. Collect the class data and record on data table
8. Answer the questions for class data

GROUP DATA TABLE:

QUESTIONS FOR GROUP DATA

1. What percentage of the male genotypes were normal? What percentage were affectedby the trait?
2. What percentage of the female genotypes were normal? What percentage were affected by the trait?
3. what percentage of the offspring were normal? What percentage were carriers? What percentage were born with sickle cell disease?

CLASS DATA TABLE

 

Introduction	Vocabulary	Micro-activity	Genetics activity
Punnett sq.	Punnett Sq. Illus.	Example of Pedigree	Assessment